Laura Miozzi

In the PhD, I focused my attention on the molecular basis of the interaction between the mycorrhizal fungus Tuber borchii and Cistus. I then investigated the microbial diversity in truffle ground soils and in orchids endophytic fungi.

Since 2004, I focused my attention on bioinformatics, working in the computational biology group at the Dep. of Genetics, Biology and Biochemistry, University of Torino; my activity was mainly focused on development of data-mining approaches for gene functional annotation, based on expression data.

Since 2006, I work as bioinformatics at the IPSP, where I study the molecular basis of plant-virus interaction, using both transcriptomic (microarray) and next generation sequencing approaches, with particular attention to the role of small RNAs. My research mainly focuses on the molecular basis of interactions between tomato plants and the viruses TSWV and TYLCSV. I also developed a bioinformatics approach for the functional annotation of tomato genes, based on conserved co-expression among the Solanaceae. I collaborate with the Dep. of Plant Biology, Univ. of Torino to study the effect of mycorrhization on  plant responses to viruses.

 

Projects

Articles and book chapters since 2008

  • 2018 - First Report of Grapevine Latent Viroid Infecting Grapevine (Vitis vinifera L.) in Italy - Rotunno S., Vaira A.M., Marian D., Schneider A., Raimondi S., Di Serio F., Navarro B., Miozzi L. - Plant Disease , volume 9
  • 2018 - Impact of high phosphorous and sodium on productivity and stress tolerance of Arundo donax plants - Cocozza C., Brilli F., Miozzi L., Pignattelli S., Rotunno S., Brunetti C., Giordano C., Pollastri S., Centritto M., Accotto G.P., Tognetti R., Loreto F. - Holzforschung ,
  • 2018 - Evidence of new viruses infecting freesia hybrids showing necrotic disease - Vaira A.M., Miozzi L., Vallino M., Carra A., Lenzi R., Salvi D., Hammond J., Pappu H.R. - Acta Horticulturae , 1193: 21-27
  • 2018 - A Short Indel-Lacking-Resistance Gene Triggers Silencing of the Photosynthetic Machinery Components Through TYLCSV-Associated Endogenous siRNAs in Tomato - Chiumenti M., Catacchio C.R., Miozzi L., Pirovano W., Ventura M., Pantaleo V. - Frontiers in plant science , 9: 1470
  • 2018 - The interaction of Lolium latent virus major coat protein with ankyrin repeat protein NbANKr redirects it to chloroplasts and modulates virus infection - Vaira A. M., Lim H. S., Bauchan G., Gulbronson C. J., Miozzi L., Vinals N., Natilla A., Hammond J. - Journal Of General Virology , 99: 730-742
  • 2017 - Deep Sequencing Data and Infectivity Assays Indicate that Chickpea Chlorotic Dwarf Virus is the Etiological Agent of the “Hard Fruit Syndrome” of Watermelon - Zaagueri T., Miozzi L., Mnari-Hattab M., Noris E., Accotto G.P., Vaira A.M. - Viruses , volume 9
  • 2017 - In silico prediction of miRNAs targeting ToLCVand their regulation in susceptible and resistant tomato plants - Tousi N., Eini O., Ahmadvand R., Carra A., Miozzi L., Noris E., Accotto G.P. - Australasian Plant Pathology , 46: 379-386
  • 2017 - Pyramiding Ty-1/Ty-3 and Ty-2 in tomato hybrids dramatically inhibits symptom expression and accumulation of tomato yellow leaf curl disease inducing viruses - Tabein S., Behjatnia S.A.A., Laviano L., Pecchioni N., Accotto G.P., Noris E., Miozzi L. - Archiv Für Phytopathologie Und Pflanzenschutz , 50: 213-227
  • 2016 - Novel functional microRNAs from virus-free and infected Vitis vinifera plants under water stress - Pantaleo V., Vitali M., Boccacci P., Miozzi L., Cuozzo D., Chitarra W., Mannini F., Lovisolo C., Gambino G. - Scientific Reports (Nature Publishing Group), 6: 20167
  • 2016 - Comparison of small RNA profiles in Nicotiana benthamiana and Solanum lycopersicum infected by polygonum ringspot tospovirus reveals host-specific responses to viral infection - Margaria P., Miozzi L., Ciuffo M., Rosa C., Axtell M.J., Pappu H.R., Turina M. - Virus Research , 211: 38-45
  • 2015 - Real-time PCR protocols for the quantification of the Begomovirus tomato yellow leaf curl Sardinia virus in tomato plants and in its insect vector - Noris E., Miozzi L. - Plant Virology Protocols New Approaches to Detect Viruses and Host Responses - Editor: Humana Press Inc., Totowa (USA), 61-72
  • 2015 - Drawing siRNAs of viral origin out from plant siRNAs libraries - Miozzi L., Pantaleo V. - Methods in Molecular Biology, 1236:111-123
  • 2015 - The first complete genome sequences of two distinct European tomato spotted wilt virus isolates - Margaria P., Miozzi L., Ciuffo M., Pappu H.r., Turina M. - Archives Of Virology , 160: 591-595
  • 2015 - Small RNA profiles of wild-type and silencing suppressor-deficient tomato spotted wilt virus infected Nicotiana benthamiana - Margaria P., Miozzi L., Rosa C., Axtell M.j., Pappu H.r., Turina M. - Virus Research , 208: 30-38
  • 2014 - The complete genome sequence of polygonum ringspot virus - Margaria P., Miozzi L., Ciuffo M., Pappu H., Turina M. - Archives Of Virology , 159:3149-3152
  • 2014 - Bioinformatics approaches for viral metagenomics in plants using short RNAs: model case of study and application to a Cicer arietinum population - Pirovano W., Miozzi L., Boetizer M., Pantaleo V. - Frontiers in Microbiology, 5:790
  • 2014 - From root to fruit: RNA-Seq analysis shows that arbuscular mycorrhizal symbiosis may affect tomato fruit metabolism - Zouari I., Salvioli A., Chialva M., Novero M., Miozzi L., Tenore G.C., Bagnaresi P., Bonfante P. - BMC Genomics , 15:221-239
  • 2014 - The arbuscular mycorrhizal symbiosis attenuates symptom severity and reduces virus concentration in tomato infected by Tomato yellow leaf curl Sardinia virus (TYLCSV) - Maffei G., Miozzi L., Fiorilli V., Novero M., Lanfranco L., Accotto G.P. - Mycorrhiza, 24:179-186
  • 2013 - Genome-wide identification of viral and host transcripts targeted by viral siRNAs in Vitis vinifera - Miozzi L., Gambino G., Burgyan J., Pantaleo V. - Molecular Plant Pathology, 14:30-43
  • 2013 - Analysis of small RNAs derived from tomato yellow leaf curl Sardinia virus reveals a cross reaction between the major viral hotspot and the plant host genome - Miozzi L., Pantaleo V., Burgyán J., Accotto G.P., Noris E. - Virus Research, 178:287-296
  • 2012 - Recombination profiles between Tomato yellow leaf curl virus and Tomato yellow leaf curl Sardinia virus in laboratory and field conditions: evolutionary and taxonomic implications - Davino S., Miozzi L., Panno S., Rubio L., Davino M., Accotto G.P. - Journal of General Virology, 93:2712-2717
  • 2011 - Arbuscular mycorrhizal symbiosis limits foliar transcriptional responses to viral infection and favors long-term virus accumulationong-term Virus Accumulation - Miozzi L., Catoni M. Fiorilli V., Mullineaux P.M. , Accotto G.P., Lanfranco L. - Molecular Plant-microbe Interactions (09067J0), 24: 1562-1572
  • 2010 - Bacterial and fungal communities associated to Tuber Magnatum-productive niches - Mello A., Miozzi L., Vizzini A., Napoli C., Kowalchuk G., Bonfante P. - Plant Biosystems, 144:323-332
  • 2010 - The complete nucleotide sequence of an isolate of Tomato yellow leaf curl Sardinia virus found in Sicily - Davino S., Miozzi L., Accotto G.P. - Archives Of Virology, 155:1539-1542
  • 2010 - Bacterial and fungal communities associated with Tuber Magnatum-productive niches - Mello A., Miozzi L., Vizzini A., Napoli C., Kowalchuk G., Bonfante P. - Plant Biosystems, 144:323-332
  • 2010 - Deep sequencing analysis of viral short RNAs from an infected Pinot Noir grapevine - Pantaleo V., Saldarelli P., Miozzi L., Giampetruzzi A., Gisel A., Moxon S., Dalmay T., Bisztray G., Burgyan J. - Virology, 408:49-56
  • 2010 - Identification of grapevine microRNAs and their targets using high-throughput sequencing and degradome analysis - Pantaleo V., Szittya G., Moxon S., Miozzi L., Moulton V., Dalmay T., Burgyan J. - Plant Journal, 62:960-976
  • 2010 - ORTom: a multi-species approach based on conserved co-expression to identify putative functional relationships among genes in tomato - Miozzi L., Provero P., Accotto G.P. - Plant Molecular Biology, 73:519-532
  • 2009 - Two new natural begomovirus recombinants associated with the tomato yellow leaf curl disease co-exist with parental viruses in tomato epidemics in Italy - Davino S., Napoli C., Dellacroce C., Miozzi L., Noris E., Davino M., Accotto G.P. - Virus Research, 143:15-23
  • 2009 - Comparative analysis of expression profiles in shoots and roots of tomato systemically infected by Tomato spotted wilt virus reveals organ-specific transcriptional responses - Catoni M., Miozzi L., Fiorilli V., Lanfranco L., Accotto G.P. - Molecular Plant-Microbe Interactions, 22:1504-1513
  • 2009 - Global and cell-type gene expression profiles in tomato plants colonized by an arbuscular mycorrhizal fungus - Fiorilli V., Catoni M., Miozzi L., Novero M., Accotto G.P., Lanfranco L. - New Phytologist, 184:975-987
  • 2008 - Functional annotation and identification of candidate disease genes by computational analisys of normal tissue gene expression data - Miozzi L., Piro R.M., Rosa F., Ala U., Silengo L., Di Cunto F., Provero P. - Plos One (00098NN), Publisher: 3(6)