Francesco Vinale

Francesco Vinale was born in Naples (Italy), the 1st Dec. 1970. He is author of 3 patents and over 100 articles published on scientific journals, reviews, book chapters, abstracts and proceedings of national and international congresses. Reviewer of several international journals and collaborates with various companies involved in the development and commercialization of biopesticides, and that develop methods to remediate contaminated soil and water by using microorganisms. He is responsible or involved in numerous research projects financed by the Italian Ministry of University and Research and the European Union. Francesco Vinale is currently Researcher at Plant Protection Institute (IPP) of the Italian National Research Council (CNR).

Research interests:
i) purification and characterization of bioactive microbial metabolites;
ii) study of the role of microbial secondary metabolites in complex plant/antagonist/pathogen interactions;
iii) study of the three-way interaction between microbial antagonists, plant and pathogens by using proteomic or metabolomic approaches;
iv) effect of bioactive microbial metabolites on plant growth promotion and induction of disease resistance;
v) application of beneficial microorganisms and / or their metabolites in agriculture and industry;
vi) study of the role of microbial metabolites involved in pathogenic events;
vii) study of the role of microbial enzymes or metabolites in decontamination of polluted soil and water (bioremediation);
viii) biochemical characterization of fungal antagonists or pathogens.


Articles and book chapters since 2008

  • 2019 - Chlamyphilone, a Novel Pochonia chlamydosporia Metabolite with Insecticidal Activity - Lacatena F., Marra R., Mazzei P., Piccolo A., Digilio M.C., Giorgini M., Woo S.L., Cavallo P., Lorito M., Vinale F. - Molecules, volume 24
  • 2019 - Salinity and Temperature Influence Growth and Pigment Production in the Marine-Derived Fungal Strain Talaromyces albobiverticillius 30548 - Venkatachalam M., Gerard L., Milhau C., Vinale F., Dufossé L., Fouillaud M. - Microorganisms, volume 9
  • 2018 - Organic Amendments, Beneficial Microbes, and Soil Microbiota: Toward a Unified Framework for Disease Suppression - Bonanomi G., Vinale F., Lorito M., Woo S.L. - Annual review of phytopathology, 56: 1-20
  • 2018 - Biochar chemistry defined by 13 C-CPMAS NMR explains opposite effects on soilborne microbes and crop plants - Bonanomi G., Ippolito F., Cesarano G., Vinale F., Lombardi N., Crasto A., Woo S.L., Scala F. - Applied Soil Ecology , 124: 351-361
  • 2018 - Inhibitory effect of trichodermanone C, a sorbicillinoid produced by Trichoderma citrinoviride associated to the green alga Cladophora sp., on nitrite production in LPSstimulated macrophages - Marra R., Nicoletti R., Pagano E., Della Greca M., Salvatore M.M., Borrelli F., Lombardi N., Vinale F., Woo S.L., Andolfi A. - Natural product research,
  • 2018 - Talarodiolide, a New 12-Membered Macrodiolide, and GC/MS Investigation of Culture Filtrate and Mycelial Extracts of Talaromyces pinophilus - Salvatore M.M., Della Greca M., Nicoletti R., Salvatore F., Vinale F., Naviglio D., Andolfi A. - Molecules , volume 23
  • 2018 - Modulation of Tomato Response to Rhizoctonia solani by Trichoderma harzianum and Its Secondary Metabolite Harzianic Acid - Manganiello G., Sacco A., Ercolano M.R., Vinale F., Lanzuise S., Pascale A., Napolitano M., Lombardi N., Lorito M., Woo S.L. - Frontiers In Microbiology , 9: 1966
  • 2018 - Root exudates of stressed plants stimulate and attract Trichoderma soil fungi - Lombardi N., Vitale S., Turrà D., Reverberi M., Fanelli C., Vinale F., Marra R., Ruocco M., Pascale A., D'Errico G., Woo S.L., Lorito M. - Molecular Plant-Microbe Interactions , 10: 982-994
  • 2018 - Biochars from olive mill waste have contrasting effects on plants, fungi and phytoparasitic nematodes - Marra R., Vinale F., Cesarano G., Lombardi N., D'Errico G., Crasto A., Mazzei P., Piccolo A., Incerti G., Woo S.L., Scala F., Bonanomi G. - Plos one, volume 13
  • 2017 - Nematicidal efficacy of new Abamectin-based products used alone and in combination with Indolebutyric acid against the root-knot nematode Meloidogyne Incognita - D'Errico G., Marra R., Vinale F., Landi S., Roversi P.F., Woo S.L. - Redia , 100: 95-101
  • 2017 - Co-Culture of Plant Beneficial Microbes as Source of Bioactive Metabolites - Vinale F., Nicoletti R., Borrelli F., Mangoni A., Parisi O.A., Marra R., Lombardi N., Lacatena F., Grauso L., Finizio S., Lorito M., Woo S.L. - Scientific Reports , volume 7
  • 2017 - Secondary metabolites from the endophytic fungus Talaromyces pinophilus - Vinale F., Nicoletti R., Lacatena F., Marra R., Sacco A., Lombardi N., D'Errico G., Digilio M.C., Lorito M., Woo S.L. - Natural product research, 31(15): 1778-1785
  • 2016 - Trichoderma and its secondary metabolites improve yield and quality of grapes - Pascale A., Vinale F., Manganiello G., Nigro M., Lanzuise S., Ruocco M., Lombardi N., Woo S.L., Lorito M., Marra R. - Crop Protection , 92: 176-181
  • 2016 - Metabolomics by Proton High-Resolution Magic-Angle-Spinning Nuclear Magnetic Resonance of Tomato Plants Treated with Two Secondary Metabolites Isolated from Trichoderma - Mazzei P., Vinale F., Woo S.l., Pascale A.,Lorito M., Piccolo A. - Journal Of Agricultural And Food Chemistry , 64: 3538-3545
  • 2016 - Cremenolide, a new antifungal, 10-member lactone from Trichoderma cremeum with plant growth promotion activity - Vinale F., Strakowska J., Mazzei P., Piccolo A., Marra R., Lombardi N., Manganiello G., Pascale A., Woo S.l., Lorito M. - Natural Product Research , 1: 7
  • 2015 - Total Synthesis and Biological Evaluation of the Tetramic Acid Based Natural Product Harzianic Acid and Its Stereoisomers - Healy A.R., Vinale F., Lorito M., Westwood N.J. - Organic Letters, 17:692-695
  • 2015 - Multiple roles and effects of a novel Trichoderma hydrophobin - Ruocco M., Lanzuise S., Lombardi N., Woo S.l., Vinale F., Marra R., Varlese R., Manganiello G., Pascale A., Scala V., Turrà D., Scala F., Lorito M. - Molecular Plant-Microbe Interactions , 28:167-169
  • 2015 - Isolation, Production And In Vitro Effects Of The Major Secondary Metabolite Produced By Trichoderma Species Used For The Control Of Grapevine Trunk Diseases. - Mutawila C., Vinale F., Halleen F., Lorito M., Mostert L. - Plant Pathology ,
  • 2014 - Metabolites produced by Gnomoniopsis castanea associated with necrosis of chestnut galls - Vinale F., Ruocco M., Manganiello G., Guerrieri E., Bernardo U., Mazzei P., Piccolo A., Sannino F., Caira S., Woo S.L., Lorito M. - Chemical And Biological Technologies In Agriculture , 1: 1-3
  • 2014 - Biopesticides and biofertilizers based on fungal secondary metabolites - Vinale F. - Journal Of Biofertilizers & Biopestic , 5: 119
  • 2014 - Trichoderma Secondary Metabolites Active on Plants and Fungal Pathogens - Vinale F., Sivasithamparam K., Ghisalberti E. L., Woo S. L., Nigro M., Marra R., Lombardi N., Pascale A., Ruocco M., Lanzuise S., Manganiello G., Lorito M. - The Open Mycology Journal, 8:127-139
  • 2014 - Trichoderma-based Products and their Widespread Use in Agriculture - Woo S. L., Ruocco M., Vinale F., Nigro M., Marra R., Lombardi N., Pascale A., Lanzuise S., Manganiello G., Lorito M. - The Open Mycology Journal, 8:71-126
  • 2014 - Effect of metabolites from different Trichoderma strains on the growth of Rosellinia necatrix, the causal agent of avocado white root rot - Arjona-Girona I., Vinale F., Ruano-Rosa D., Lorito M., Lopez-Herrera C.J. - European Journal Of Plant Pathology , 140:385-397
  • 2014 - A novel fungal metabolite with beneficial properties for agricultural applications - Vinale F., Manganiello G., Nigro M., Mazzei P., Piccolo A., Pascale A., Ruocco M., Marra R., Lombardi N., Lanzuise S., Varlese R., Cavallo P., Lorito M., Woo S.l. - Molecules , 19:9760-9772
  • 2013 - Harzianic acid: a novel siderophore from Trichoderma harzianum - Vinale F., Nigro M., Sivasithamparam K., Ghisalberti E.L., Flematti G., Ruocco M., Varlese R., Marra R., Lanzuise S., Eid A., Woo S.L., Lorito M. - Fems Microbiology Letters , 347:123-129
  • 2012 - Analysis of apple fruit proteomes induced by alternative post-harvest treatments. - Eid A.M.E., Sanzani S.E., Woo S.l., Vinale F., Lanzuise S., Nigro M., Varlese R., Marra R., Matteoli V., Manganiello G., Pascale A., Stellitano D., Lorito M. - Journal of Plant Pathology , 94(4):S4.62
  • 2012 - Trichoderma secondary metabolites that affect plant metabolism - Vinale F., Sivasithamparam K., Ghisalberti E.l., Ruocco M., Woo S., Lorito M. - Natural Product Communications , 7:1545-1550
  • 2012 - Cerinolactone, a hydroxy-lactone derivative from Trichoderma cerinum - Vinale F., Girona I.a., Nigro M., Mazzei P., Piccolo A., Ruocco M., Woo S., Rosa D.r., Herrera C.l:, Lorito M. - Journal of Natural Products , 75:103-106
  • 2012 - Classical and modern techniques to assess the effects of crop rotation on the soil microbial community - Varlese D.G.C., Ruocco M., Vinale F., Lanzuise S., Nigro M., Eid A.M.E., Pascale A., Manganiello G., Matteoli V., Stellitano D., Marra R., Lorito M., Woo S.l. - Journal of Plant Pathology , 94:S4.83
  • 2012 - Role of Trichoderma secondary metabolites in plant interactions: the metabolic changes in Arabidopsis thaliana - Nigro M., Vinale F., Ruocco M., Woo S.l., Lanzuise S., Marra R. , Eid A., Varlese R., Matteoli V., Manganiello G., Pascale A., Stellitano D., Perera V. , Grant M., Lorito M. - Journal of Plant Pathology , 94:S4.71
  • 2009 - Identification of a new biocontrol gene in Trichoderma atroviride: the role of an ABC transporter membrane pump in the interaction with different plant-pathogenic fungi - Ruocco M., Lanzuise S., Vinale F., Marra R., Turrà D., Woo S.l., Lorito M. - Molecular Plant-Microbe Interactions , 22:291-301
  • 2009 - Induction Of Systemic Resistance: A Main Mechanism Of Action Of Biopesticides Based On Antagonistic Fungi. - Vinale F., Woo S.l., Ruocco M., Marra R., Lanzuise S., Scala F., Cavallo P., Lorito M. - Petria , 19:70-72
  • 2008 - Cloning and functional characterization of BcatrA, a gene encoding an ABC transporter of the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) - Del Sorbo G., Ruocco M., Schoonbeek H., Scala F., Pane C., Vinale F., De Waard M.a. - Mycological Research , 112: 737-746