Luisa Rubino

My research focuses on positive strand RNA plant virus replication. A combination of genomics and microscopy approaches is used to address fundamental problems using model systems. Tombusviruses are used as model viruses to identify the replication molecular mechanisms of viral genomic RNA and of subviral RNA molecules (satellite and defective interfering RNAs) in plants. Saccharomyces cerevisiae is also used as a model host to investigate virus-host interactions and to identify host factors involved in tombusvirus replication. The group is involved in the analysis of targeting and anchoring of the virus replicase proteins to cell membranes and of the formation of the viral replication complex. Approaches that have practical relevance to the development of new antiviral strategies are also explored.

Projects

Articles and book chapters since 2008

  • 2019 - Additional changes to taxonomy ratified in a special vote by the International Committee on Taxonomy of Viruses (October 2018) - Siddell S.G., Walker P.J., Lefkowitz E.J., Mushegian A.R., Adams M.J., Dutilh B.E., Gorbalenya A.E., Harrach B., Harrison R.L., Junglen S., Knowles N.J., Kropinski A.M., Krupovic M., Kuhn J.H., Nibert M., Rubino L., Sabanadzovic S., Sanfacon H., Simmonds P., Varsani A., Zerbini F.M., Davison A.J. - Archives of virology, 164: 943-946
  • 2018 - Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2018) - King A.M.Q., Lefkowitz E.J., Mushegian A.R., Adams M.J., Dutilh B.E., Gorbalenya A.E., Harrach B., Harrison R.L., Junglen S., Knowles N.J., Kropinski A.M., Krupovic M., Kuhn J.H., Nibert M.L., Rubino L., Sabanadzovic S., Sanfacon H., Siddell S.G., Simmonds P., Varsani A., Zerbini F.M. Davison A.J. - Archives of virology, 163: 2601-2631
  • 2017 - Small Circular Satellite RNAs - Navarro B., Rubino L., Di Serio F. - Viroids and Satellites, 659-669
  • 2017 - Heterologous expression of carnation Italian ringspot virus p36 protein enhances necrotic cell death in response to acetic acid in Saccharomyces cerevisiae - Rubino L., Guaragnella N., Giannattasio S. - Mechanisms of ageing and development, 161: 255-261
  • 2017 - Biology of Satellites - Rubino L. - in: Viroids and Satellites, 567-575
  • 2014 - Tombusvirus-induced multivesicular bodies: Origin and role in virus-host interaction - Rubino L., Russo M., Martelli G.P. - Plant Virus-Host Interactions. Molecular Approaches and Viral Evolution,
  • 2012 - Potexviruses and Carlaviruses – Short Filamentous Viruses - Martelli G.P., Rubino L. - Encyclopedia of Life Sciences , online
  • 2012 - Presence of Tobacco Ringspot Virus in Aemonium - Sorrentino R., Alioto D., Russo M., Rubino L. - Journal of Plant Pathology, 94:S4.85
  • 2012 - Tepovirus, a new genus in the family Betaflexiviridae - Rubino L., Russo M., De Stradis A., Martelli G.P. - Archives of Virology, 157:1629-1633
  • 2012 - A single amino acid substitution in the ORF1 of Cymbidium ringspot virus determines the accumulation of two satellite RNAs in Virus research - Rubino L., Russo M. - Virus Research, 168:84-87
  • 2012 - Family Tombusviridae. - Rochon D'A., Lommel S., Martelli G.P., Rubino L., Russo. M - Virus Taxonomy. Ninth Report of the International Committee on Taxonomy of Viruses, 1081 -1108
  • 2011 - Disease note: First report of a resistance-breaking strain of Tomato spotted wilt virus from gerbera jamesonii in Apulia, Southern Italy. - Spanò R., Mascia T., De Lucia B., Torchetti E.M., Rubino L., Gallitelli D. - Journal of Plant Pathology, 93-S4.63
  • 2011 - Presenza di Tomato spotted wilt virus e ‘Candidatus Phytoplasma asteris’ su piante di gerbera in Puglia - Spanò R., Marzachì C., Mascia T., De Lucia B., Bubici G., Torchetti E.M., Rubino L., Gallitelli D. - Protezione Delle Colture , 4: 79-83
  • 2011 - Eggplant mottled dwarf virus - Martelli G.P., Russo M., Rubino L. - Aab Descriptions Of Plant Viruses , Publisher: AAB
  • 2011 - Family Tombusviridae - Rochon D’A., Lommel S., Martelli G.P., Rubino L., Russo M. - Virus Taxonomy. Ninth Report Of The International Committee On Taxonomy Of Viruses , Publisher: King A., Adams M.J., Carstens E.B., Lefkowitz E.
  • 2011 - Generation of virus-like particles in plants expressing the capsid protein of Cymbidium Ringspot Virus - Rubino L., De Stradis A., Russo M., Martelli G. P. - Journal Of Plant Pathology (00077NN), 93: 751-756
  • 2011 - First report of a resistance-greaking strain of Tomato spotted wilt virus from Gerbera jamesonii in Apulia, Southern Italy - Spano' R., Mascia T., De Lucia B., Torchetti E.M., Rubino L., Gallitelli D. - Journal Of Plant Pathology (00077NN), Publisher: 93
  • 2010 - Properties of a novel satellite RNA associated with tomato bushy stunt virus infections - Rubino L., Russo M. - Journal Of General Virology, 91:2393-2401
  • 2009 - The complete nucleotide sequence of potato virus T - Russo M., Rubino L., De Stradis A., Martelli, G.P. - Archives of Virology, 154:321-325
  • 2008 - Molecular and ultrastructural properties of maize white line mosaic virus - Russo M., De Stradis A., Boscia D., Rubino L., Redinbaugh M.g., Abt J.j., Martelli G.p. - Journal Of Plant Pathology (00077NN), 90: 363-369
  • 2008 - Interactions between replicase proteins and host cell membranes in positive-strand RNA plant virus replication - Rubino, L. & Russo, M. - “biology Of Plant-microbe Interactions Cd, Vol. 6 , Publisher: International Society for molecular Plant -microbe
  • 2008 - Necrovirus - Rubino L., Martelli G.P. - Encyclopedia Of Virology, 5 Vols , Publisher: Elsevier
  • 2008 - Analysis of sequences in the Cymbidium ringspot virus replicase protein p33 that promote targeting and anchoring to endoplasmic reticulum membranes - Rubino L., Vernile P., Russo M., - Journal Of Plant Pathology (00077NN), 90: 575-580